The following data are from Gennings, Chinchilli, and Carter, (1989). An in vitro toxicity study of isolated hepatocyte suspensions was conducted to study the impact of combining carbon tetrachloride (CCl4) and chloroform (CHCl3) on the toxicity of cells. Cell toxicity was measured by the amount of lactic dehydrogenase (LDH) enzyme leakage. The study involved randomly assigning four flasks to each of the 16 treatments obtained by combining four levels of CCl4 (0, 1.0, 2.5, and 5.0 mM) with four levels of CHCl3 (0, 5, 10, and 25 mM). The percentage of LDH leakage from the cells in each of the 64 flasks was measured just prior to applying the treatment to the flasks and at .01, .25, .5, 1, 2, and 3 hours after applying the treatment. The percentages of LDH leakage are given in the following table.
a. Plot the mean percentages of LDH leakage by time for the 16 treatments. Does there appear to be an effect due to increasing the level of CCl4 or CHCl3?
b. From the plot, does there appear to be an increase in the mean percentages of leakage as time after treatment increases?
c. Plot a profile plot of the mean percentage of LDH leakage separately for each time period. Does there appear to be a difference in the profile plots?
Delivering a high-quality product at a reasonable price is not enough anymore.
That’s why we have developed 5 beneficial guarantees that will make your experience with our service enjoyable, easy, and safe.
You have to be 100% sure of the quality of your product to give a money-back guarantee. This describes us perfectly. Make sure that this guarantee is totally transparent.Read more
Each paper is composed from scratch, according to your instructions. It is then checked by our plagiarism-detection software. There is no gap where plagiarism could squeeze in.Read more
Thanks to our free revisions, there is no way for you to be unsatisfied. We will work on your paper until you are completely happy with the result.Read more
Your email is safe, as we store it according to international data protection rules. Your bank details are secure, as we use only reliable payment systems.Read more
By sending us your money, you buy the service we provide. Check out our terms and conditions if you prefer business talks to be laid out in official language.Read more